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Samira S Valvassori Selected Research

Dextroamphetamine (Dexedrine)

1/2021Role of epigenetic regulatory enzymes in animal models of mania induced by amphetamine and paradoxical sleep deprivation.
1/2020The GLP-1 receptor agonist liraglutide reverses mania-like alterations and memory deficits induced by D-amphetamine and augments lithium effects in mice: Relevance for bipolar disorder.
11/2019Coadministration of lithium and celecoxib reverses manic-like behavior and decreases oxidative stress in a dopaminergic model of mania induced in rats.
5/2019Effects of lithium and valproate on ERK/JNK signaling pathway in an animal model of mania induced by amphetamine.
1/2019Coadministration of lithium and celecoxib attenuates the behavioral alterations and inflammatory processes induced by amphetamine in an animal model of mania.
1/2018The Effects of Histone Deacetylase Inhibition on the Levels of Cerebral Cytokines in an Animal Model of Mania Induced by Dextroamphetamine.
8/2015Lithium modulates the production of peripheral and cerebral cytokines in an animal model of mania induced by dextroamphetamine.
1/2014Histone deacetylase activity and brain-derived neurotrophic factor (BDNF) levels in a pharmacological model of mania.
12/2013Sodium butyrate reverses the inhibition of Krebs cycle enzymes induced by amphetamine in the rat brain.
9/2013Evaluation of acetylcholinesterase in an animal model of mania induced by D-amphetamine.
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Samira S Valvassori Research Topics

Disease

61Mania (Manias)
01/2022 - 05/2006
35Bipolar Disorder (Manic Depressive Psychosis)
01/2022 - 06/2006
8Attention Deficit Disorder with Hyperactivity (Attention Deficit Hyperactivity Disorder)
03/2011 - 08/2007
5Cognitive Dysfunction
01/2022 - 08/2015
5Mental Disorders (Mental Disorder)
01/2022 - 07/2007
5Schizophrenia (Dementia Praecox)
08/2021 - 06/2006
5Body Weight (Weight, Body)
01/2021 - 11/2008
5Meningitis
01/2017 - 03/2013
5Mood Disorders (Mood Disorder)
08/2015 - 06/2006
3Sleep Deprivation
01/2021 - 06/2015
3Inflammation (Inflammations)
01/2020 - 11/2014
3Mitochondrial Diseases (Mitochondrial Disease)
02/2014 - 10/2010
2Sepsis (Septicemia)
01/2022 - 09/2007
2Memory Disorders (Memory Loss)
01/2020 - 07/2007
2Pneumococcal Meningitis (Streptococcus pneumoniae Meningitis)
01/2017 - 08/2015
2Obesity
08/2013 - 12/2011
2Depressive Disorder (Melancholia)
02/2013 - 09/2009
1Infections
01/2022
1Maple Syrup Urine Disease
01/2021
1Tyrosinemias (Tyrosinemia)
01/2017

Drug/Important Bio-Agent (IBA)

31LithiumIBA
01/2020 - 06/2006
21Valproic Acid (Depakote)FDA LinkGeneric
12/2019 - 06/2006
20Ouabain (G Strophanthin)IBA
01/2022 - 12/2009
20Dextroamphetamine (Dexedrine)FDA LinkGeneric
01/2021 - 05/2006
17Brain-Derived Neurotrophic Factor (BDNF)IBA
01/2021 - 06/2006
16Amphetamine (Amfetamine)FDA LinkGeneric
01/2021 - 05/2006
13EnzymesIBA
01/2022 - 05/2006
11Histone Deacetylase InhibitorsIBA
01/2021 - 06/2011
9Butyric Acid (Butanoic Acid)IBA
01/2018 - 12/2011
9Methylphenidate (Ritalin)FDA LinkGeneric
03/2011 - 05/2007
8AntioxidantsIBA
01/2021 - 05/2006
8Nerve Growth Factors (Neurotrophins)IBA
12/2019 - 04/2008
7Histone Deacetylases (Histone Deacetylase)IBA
01/2021 - 06/2011
7Nerve Growth Factor (NGF)IBA
12/2019 - 06/2006
6Proteins (Proteins, Gene)FDA Link
01/2019 - 11/2008
6TamoxifenFDA LinkGeneric
01/2019 - 04/2011
5KetamineFDA LinkGeneric
08/2021 - 04/2009
5Glial Cell Line-Derived Neurotrophic Factor (GDNF)IBA
12/2019 - 02/2015
5CytokinesIBA
01/2018 - 01/2014
4ATPase Inhibitory ProteinIBA
11/2014 - 12/2009
4Creatine Kinase (Creatine Phosphokinase)IBA
06/2011 - 02/2008
3salicylhydroxamic acid (SHAM)IBA
01/2022 - 09/2007
3Antipsychotic Agents (Antipsychotics)IBA
01/2021 - 07/2007
3Interleukin-6 (Interleukin 6)IBA
01/2020 - 01/2014
3Celecoxib (Celebrex)FDA Link
11/2019 - 01/2019
3Adenosine Triphosphatases (ATPase)IBA
11/2017 - 04/2009
3Protein Kinase CIBA
11/2017 - 12/2012
3Pharmaceutical PreparationsIBA
09/2017 - 12/2011
3AcetylcholinesteraseIBA
08/2015 - 09/2013
3Biological ProductsIBA
01/2014 - 03/2013
3N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA
04/2009 - 01/2008
2Antidepressive Agents (Antidepressants)IBA
01/2022 - 09/2009
2MethyltransferasesIBA
08/2021 - 01/2021
2Folic Acid (Vitamin M)FDA LinkGeneric
08/2021 - 01/2020
2DNA (Deoxyribonucleic Acid)IBA
01/2021 - 01/2017
2Biomarkers (Surrogate Marker)IBA
01/2020 - 01/2019
2Excipients (Suspending Agents)IBA
01/2019 - 01/2018
2Glycogen Synthase (Synthase I)IBA
01/2018 - 12/2012
2Neuroprotective AgentsIBA
01/2017 - 01/2008
2Free RadicalsIBA
01/2017 - 05/2008
2CorticosteroneIBA
01/2017 - 04/2009
2Adrenocorticotropic Hormone (ACTH)FDA Link
01/2017 - 04/2009
2Thiobarbituric Acid Reactive SubstancesIBA
01/2016 - 03/2014
2Histones (Histone)IBA
08/2015 - 03/2013
2Acetylcysteine (Siran)FDA LinkGeneric
06/2015 - 05/2008
2Deferoxamine (Desferal)FDA LinkGeneric
06/2015 - 05/2008
2fenproporexIBA
04/2014 - 03/2014
2Methamphetamine (Desoxyn)FDA LinkGeneric
01/2013 - 08/2012
2BB Form Creatine KinaseIBA
02/2010 - 02/2008
2Reactive Oxygen Species (Oxygen Radicals)IBA
06/2009 - 06/2006
2Superoxide DismutaseIBA
05/2009 - 05/2006
2CatalaseIBA
05/2009 - 05/2006
1N 30IBA
01/2022
1Imipramine (Janimine)FDA LinkGeneric
01/2022
1KynurenineIBA
11/2021
1Haloperidol (Haldol)FDA LinkGeneric
01/2021
1AcidsIBA
01/2021
1Branched-Chain Amino AcidsIBA
01/2021
1Oxidoreductases (Dehydrogenase)IBA
01/2021
1Cyclooxygenase 2 (Cyclooxygenase-2)IBA
10/2020
1Arachidonic AcidsIBA
10/2020
1Arachidonic Acid (Vitamin F)IBA
10/2020
1Prostaglandins EIBA
10/2020
1Phospholipases A2 (Phospholipase A2)IBA
10/2020
1LiraglutideFDA Link
01/2020
1Glucagon-Like Peptide-1 ReceptorIBA
01/2020
1neurotrophin 4IBA
12/2019
1N- (4- methoxybenzyl)- N'- (5- nitro- 1,3- thiazol- 2- yl)ureaIBA
04/2019
1MicroRNAs (MicroRNA)IBA
01/2019
1ResveratrolIBA
01/2019
1InflammasomesIBA
01/2019
1Cyclooxygenase 2 Inhibitors (COX-2 Inhibitors)IBA
01/2019
1Mitochondrial DNA (mtDNA)IBA
12/2017
1Tyrosine Transaminase (Tyrosine Aminotransferase)IBA
01/2017
1Tyrosine (L-Tyrosine)FDA Link
01/2017
1Omega-3 Fatty Acids (Omega 3 Fatty Acids)IBA
01/2017

Therapy/Procedure

3Therapeutics
01/2022 - 03/2014
1Ligation
01/2022
1Intraperitoneal Injections
08/2021
1Drug Therapy (Chemotherapy)
01/2020